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As economic pressures increase, stakeholders at every level of the health care system are discovering that trying to do the same thing, but on a lower budget, will only take them so far. New models of health care delivery are emerging, old models are under siege, and financial risk for the costs of care is being pushed outward from insurers to providers. Will these new models for care delivery and for payment endure? And how can academic medical centers adapt? This live-streamed meeting explores emerging risk in health care through three sessions: disruptive new ventures, innovative payment methodologies, and creative care delivery models.